Independent Research
Master's Graduate Students co-authors are underlined, and Undergraduate Student co-authors are bold.
8. Ehlbeck, J.T.; Grimard, D.M.; Hacker, R.M.; Garcia, J.A.; Wall, B.J.; Bothwell, P.J.; Jones, M.A.; Webb, M.I. "Finding the Best Location: Improving the Anti-Amyloid Ability of Ruthenium(III) Complexes with Pyridine Ligands" Journal of Inorganic Biochemistry 2024, 250, 112424. *Invited Submission for special issue: Recent Advances in BioInorganic Chemistry from CanBic8. Link
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7. Webb, M.I. (2023). "The Design of Metal Complexes to Target the Amyloid-β Peptide in Alzheimer's Disease" In Encyclopedia of Inorganic and Bioinorganic Chemistry, R.A. Scott (Ed.) Link *Invited Submission*
6. Mensah, S.; Rosenthal, J.D.; Dagar, M.; Brown, T.; Mills, J.J.; Hamaker, C.G.; Ferrence, G.M.; Webb, M.I. "A Ru(II)-Arene-Ferrocene Complex With Promising Antibacterial Activity" Dalton Transactions 2022, 51, 17609-17619. Link |
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5. Yawson, G. K.; Will, M.F.; Huffman, S. E.; Strandquist, E.T.; Bothwell, P.J.; Oliver, E.B.; Platt, D.C.; Apuzzo, C.F.; Weitzel, C.S.; Jones, M.A.; Ferrence, G.M.; Hamaker, C.G.; Webb, M.I. “A Dual-Pronged Approach: A Ruthenium(III) Complex That Modulates Amyloid-β Aggregation and Disrupts Its Formed Aggregates” Inorganic Chemistry 2022, 61, 2733-2744. Link |
4. Meiss, C.J.; Bothwell, P.J.; Webb, M.I. "Ruthenium(II)-Arene Complexes With Chelating Quinoline Ligands as Anti-Amyloid Agents" Canadian Journal of Chemistry, 2022, 100, 18-24. Link |
3. Wall, B.J.#; Will, M.F.#; Yawson, G.K.; Bothwell, P.J.; Platt, D.C.; Apuzzo, C.F.; Jones, M.A.; Ferrence, G.M.; Webb, M.I. “Importance of Hydrogen Bonding: Structure-Activity Relationships of Ruthenium(III) Complexes with Pyridine-based Ligands for Alzheimer's Disease Therapy" Journal of Medicinal Chemistry 2021, 64, 10124-10138.
(# the author's contributed equally to the paper) Link
2. Yawson, G.K.; Huffman, S.E.; Fisher, S.F.; Bothwell, P.J.; Platt, D.C.; Jones, M.A.; Ferrence, G.M.; Hamaker, C.G.; Webb, M.I. “Ruthenium(III) complexes with imidazole ligands that modulate the aggregations of the amyloid-β peptide via hydrophobic interactions” Journal of Inorganic Biochemistry 2021, 214, 111303. Link
1. Huffman, S.E.#; Yawson, G.K.#; Fisher, S.F.; Bothwell, P.J.; Platt, D.C.; Jones, M.A.; Hamaker, C.G.; Webb, M.I. “Ruthenium(III) Complexes Containing Thiazole-Based Ligands That Modulate Amyloid-β Aggregation” Metallomics 2020, 12, 491-503. Featured on the back cover!
(# the author's contributed equally to the paper) Link
Mentored Studies
16. Safaei, E.; Balaghi, S.E.; Chiang, L.; Clarke, R.M.; Martelino, D.; Webb, M.I.; Wong, E.W.Y.; Savard, D.; Walsby, C.J.; Storr, T. “Stabilization of different redox levels of a tridentate benzoxazole amidophenoxide ligand when bound to Co(III) or V(V)” Dalton Trans. 2019, 48, 13326-13336. Link
15. Webb, M.I.; Walsby, C.J. “Albumin binding and ligand-exchange processes of the Ru(III) anticancer agent NAMI-A and its bis-DMSO analogue determined by ENDOR spectroscopy” Dalton Trans. 2015, 44, 17482-17493. Featured on the front cover of issue 40! Link
14. Jones, M.J.; Mu, C.; Wang, M.C.P.; Webb, M.I.; Walsby, C.J.; Storr, T. “Modulation of the Aβ peptide aggregation pathway by KP1019 limits Aβ-associated neurotoxicity” Metallomics 2015, 7, 129-135. Link
13. Lo, S.Y.; Säbel, C.E.; Webb, M.I.; Walsby, C.J.; Siemann, S. “High Metal Substitution Tolerance of Anthrax Lethal Factor and Characterization of its Active Copper-substituted Analogue” J. Inorg. Biochem. 2014, 140: 12-22. Link
11. Webb, M.I.; Wu, B.; Jang, T.; Chard, R.A.; Wong, E.W.Y.; Wong, M.Q.; Yapp, D.T.T.; Walsby C.J. “Increasing the Bioavailability of RuIII Anticancer Complexes through Hydrophobic Albumin Interactions” Chem. Eur. J. 2013, 19: 17031-17042. Link
Featured on Global Medical Discovery
Featured on Global Medical Discovery
10. Webb, M.I.; Walsby, C.J. “Intra-cellular Behaviour of Ruthenium Anticancer Complexes, Determined by EPR Spectroscopy” Metallomics 2013, 5: 1624-1633. Link
9. Dunn, T.J.; Chiang, L.; Ramogida, C.F.; Hazin, K.; Webb, M.I.; Katz, M.J.; Storr, T. “Class III Delocalization and Exciton Coupling in a Bimetallic Bis-ligand Radical Complex” Chem. Eur. J. 2013, 19: 9606-9618. Link
8. Dunn, T.J.; Webb, M.I.; Hazin, K.; Verma, P.; Wasinger, E.C.; Shimazaki, Y.; Storr, T. “The Electronic Structure of a Doubly Oxidized Ni Bis-Phenoxyl Radical Complex” Dalton Trans. 2013, 42: 3950-3956. Link
7. Dunn, T.J.; Chiang, L.; Ramogida, C.F.; Webb, M.I.; Savard, D.; Sakaguchi, M.; Ogura, T.; Shimazaki, Y.; Storr, T. “Non-Innocent Ligand Behaviour of a Bimetallic Cu Complex Employing a Bridging Catecholate” Dalton Trans. 2012, 41: 7905-7914. Link
6. Simmons, J.M.; Yildirim, T.; Hamaed, A.; Antonelli, D.M.; Webb, M.I.; Walsby, C.J. “Direct Observation of Activated Hydrogen Bonding to a Supported Organometallic Compound at Room Temperature” Chem. Eur. J. 2012, 18: 4170-4173. Link
5. Webb, M.I.; Chard, R.A.; Al-Jobory, Y.M.; Jones, M.R.; Wong, E.W.Y.; Walsby, C.J. “Pyridinium Analogs of the Antimetastatic Ru(III) Complex NAMI-A Targeting Non-Covalent Interactions with Albumin” Inorg. Chem. 2012, 51: 954-966. Link
4. Sherren, C.N.; Mu, C.; Webb, M.I.; McKenzie, I.; McCollum, B.M.; Brodovitch, J.-C.; Percival, P.W.; Storr, T.; Seddon, K.R.; Clyburne, J.A.C.; Walsby, C.J. “Merging the chemistry of electron-rich olefins with imidazolium ionic liquids: radicals and hydrogen-atom adducts.” Chem. Sci. 2011, 2: 2173-2177. Link
3. Webb, M.I.; Walsby, C.J. “Control of Ligand Exchange Processes and the Oxidation State of the Antimetastatic Ru(III) Complex NAMI-A Through Interactions with Albumin.” Dalton Trans. 2011, 40: 1322-1331. Link
2. Cetinbas, N.; Webb M.I.; Dubland, J.A; Walsby, C.J. “Serum-protein interactions with anticancer Ru(III) complexes KP1019 and KP418 characterized by EPR” J. Biol. Inorg. Chem. 2010, 15: 131-145. Link
1. Hoang, T.K.A.; Webb, M.I.; Mai, H.V.; Hamaed, A.; Walsby, C.J.; Trudeau, M.; Antonelli, D.M. “Design and Synthesis of Vanadium Hydrazide Gels for Kubas-Type Hydrogen Adsorption: A New Class of Hydrogen Storage Materials” J. Am. Chem. Soc. 2010, 132: 11792–11798. Link